🔬 A Clinical Companion to the Burn Protocol

Burn Science

Going deeper than the family module — the clinical questions behind burn prevention, answered with current evidence and 3D anatomy. Built for our clinical partners to explore, pressure-test, and refine.

📋 Draft for discussion — prepared for the Burn Prevention brain-share with Dr. Lourdes Castañón (Burn, Banner–University Medical Center), Kathy, and the intern team.
How to use this page: each question below expands into a plain-English answer, the evidence behind it, a link to a 3D model in our 360 Human Explorer, and a discussion prompt for the meeting. Where a number deserves an expert's eye, we've flagged it — your feedback becomes the next version.
1Prevention

Are 90% of burns really preventable?

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Short answer: the large majority are. The World Health Organization states plainly that "burns are preventable," and points to high-income countries that have driven down burn deaths dramatically through known measures (smoke alarms, hot-water limits, safer cookstoves, legislation). Burn-prevention programs commonly cite figures up to ~90% preventable as a rallying number for exactly this reason.

The honest nuance for the meeting: "90%" is a public-health prevention message, not a single peer-reviewed constant — the exact preventable fraction varies by burn type, age, and setting. What's rigorously supported: most burns follow predictable, modifiable patterns (scalds in ages 1–4, cooking, hot tap water), which is what makes prevention so high-yield.

For Dr. Castañón: what preventable fraction does Banner's burn service see in practice — and which one or two upstream changes would move it most?
Sources: WHO Burns fact sheet; American Burn Association prevention resources; Palmieri 2024.
2Depth & classification

What is a 4th-degree burn? (and the full depth scale)

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Burn "degree" describes how deep the injury goes:

1st degreeEpidermis only. Red, painful, no blisters (e.g., mild sunburn). Not counted in burn size.
2nd degreeInto the dermis. Blisters, very painful (partial-thickness).
3rd degreeThrough the dermis to fat. White/leathery or cherry-red; often needs grafting (full-thickness).
4th degreeBeyond skin — into muscle, tendon, even bone. Limb- and life-threatening.

So a 4th-degree burn is the deepest classification: the injury extends past all skin layers into the soft tissue and structures beneath. Palmieri (2024): "Fourth-degree burns extend beyond the skin, involving soft tissues including muscle and even bony structures."

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360 Human Explorer → "Burns" and the Epidermis Cell Layer models show these planes in 3D. Open the Explorer → (Integumentary System · model be=5xdS)
Discussion: which model best shows students the jump from 3rd to 4th degree — and should we build a labeled "burn depth" tour inside the Explorer?
Sources: Palmieri 2024 (Semin Plast Surg); ABA.
3Burn size

What does "a 50% burn" mean?

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It means 50% of the body's total surface area (TBSA) is burned — a measure of extent, separate from depth. TBSA drives fluid resuscitation and transfer decisions, so getting it right matters.

Two bedside tools: the Rule of Nines (adult: head 9%, each arm 9%, front torso 18%, back 18%, each leg 18%, genitals 1%) and the palm method (the patient's palm + fingers ≈ 1% TBSA). Crucially, only partial- and full-thickness (2nd–4th degree) burns count — superficial 1st-degree is excluded. Children use the Lund-Browder chart because their head is a much larger share of TBSA.

Teaching idea: a "map the burn" interactive on the body — could interns practice Rule of Nines vs. Lund-Browder on the same patient?
Sources: StatPearls (Parkland Formula / Burn Fluid Resuscitation); Palmieri 2024 (palm method, Lund-Browder).
4Anatomy

Skin depth varies across the body — why it matters

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Skin isn't uniform. It's thinnest on the eyelids and thickest on the palms and soles, and — critically — children's skin is much thinner than adults'. Palmieri: a child's thinner skin "will develop a third-degree burn at lower temperatures and over a shorter exposure period than for adults." Same heat, deeper burn.

That's the bridge from prevention to physiology: it's why 120°F vs. 140°F tap water changes a child's outcome from minutes to seconds, and why the same spill is a deeper injury on a toddler than on an adult.

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360 Human Explorer → Epidermis Cell Layers (Light & Dark Skin) and Skin Tissue show the epidermis–dermis–subcutis planes. Open the Explorer → (be=727O / 727N · Skin Tissue be=72L1)
Discussion: should the Explorer's skin models carry a "burn depth overlay" so a 2nd vs 3rd vs 4th degree is visible against the real layers?
Sources: Palmieri 2024 (pediatric skin thickness, temperature/time table).
5Physiology

The role plasma plays in the burn world

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A major burn isn't just a skin wound — it's a whole-body fluid emergency. Inflammatory mediators make capillaries leaky, so fluid, electrolytes, and plasma proteins pour out of the bloodstream into the tissues, peaking around 8–12 hours. The result is "burn shock" — dangerous low blood volume even though the patient is swelling.

That's why resuscitation is central. The Parkland formula starts crystalloid (Lactated Ringer's, ~4 mL × kg × %TBSA over 24h, titrated to urine output). Because so much plasma is lost, guidelines increasingly add colloid/plasma within the first 8–24 hours to cut total fluid needs — and newer burn-center work is testing early plasma to fight the leak itself.

For Dr. Castañón: where does Banner sit on early-plasma vs. crystalloid-first resuscitation, and what would you want families/first-responders to understand about "why the swelling"?
Sources: StatPearls (Parkland Formula); ACS "Early Plasma in Burn Resuscitation"; Palmieri 2024.
6Airway

Inhalation injury — the hidden killer

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Many burn deaths aren't from the skin burn — they're from what was breathed in. Palmieri groups inhalation injury into three types: (1) toxic gases / carbon monoxide / hypoxia, (2) upper-airway swelling from heat, and (3) lower-airway damage from toxic smoke particulates.

Key clinical points: children sustain inhalation injury at higher rates than adults; a pulse oximeter can read falsely normal with carbon-monoxide poisoning (needs co-oximetry); and airway swelling develops over hours, so serial airway checks are essential. This is the physiology behind "get low, get out, and why working smoke alarms save lives."

Discussion: should the family module add a short "smoke & airway" explainer that connects the smoke-alarm pillar to what inhalation actually does?
Sources: Palmieri 2024 (three categories of inhalation injury, CO & co-oximetry).
7Mechanism

Why do electrical burns injure inside the body, not just the skin?

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Because the damage is caused by current traveling through the body, not just heat on the surface. Electricity enters, follows the path of least resistance through muscles, nerves, and blood vessels, and generates heat internally along the way — so the entry and exit wounds on the skin can look small while deep tissue is devastated. Clinicians call it the "iceberg" phenomenon: what you see is a fraction of the injury.

That deep, hidden damage drives the real dangers: rhabdomyolysis (muscle breakdown that can injure the kidneys), cardiac arrhythmias, and compartment syndrome. It's why any significant electrical contact warrants evaluation even when the skin looks fine — a powerful teaching contrast for interns.

For Dr. Castañón: a case example of "small skin, big inside" would land hard with students — is there one you'd be open to sharing (de-identified)?
Sources: Merck Manual (Electrical Injuries); StatPearls (Electrical Injuries); "Electrical Injuries: The Iceberg Phenomenon."

See it in 3D — the 360 Human Explorer

Our 360 Human Explorer (Integumentary System, 123 lessons) already carries the exact models to demonstrate these answers. Open it and search these:

Burns — burn injury in tissue (be=5xdS)
Epidermis Cell Layers — light & dark skin (be=727O / 727N)
Skin Tissue — epidermis → dermis → subcutis (be=72L1)
Sunburn — UV injury to the epidermis (be=72Ls)
Open the 360 Human Explorer →

Sources

  1. Palmieri, T.L. (2024). Initial Pediatric Burn Management: A Practical Guide. Seminars in Plastic Surgery, 38:88–92.
  2. Fallat, M.E., et al. (2026). Current Status of US Children's Burn Care and Opportunities for Change. Annals of Surgery Open, 1:e641.
  3. StatPearls — Parkland Formula & Burn Fluid Resuscitation (NCBI Bookshelf).
  4. American College of Surgeons — Challenging Legacy Burn Resuscitation Paradigms with Fluid Restriction and Early Plasma.
  5. Merck Manual (Professional) & StatPearls — Electrical Injuries; "Electrical Injuries: The Iceberg Phenomenon."
  6. World Health Organization — Burns fact sheet; American Burn Association — Prevention & Incidence resources.
⚕️ Educational draft, not a clinical protocol. This companion is for professional discussion and program design; it does not replace clinical judgment, institutional protocols, or emergency care. Figures flagged for expert review will be updated from this meeting's input. In an emergency, call 911.